Monster.com
Comprehensive national job site (also United Kingdom and Canada) with tens of thousands of searchable job listings.

CareerBuilder.com
This valuable site adds a meta search engine to search multiple job sites in addition to its own job site.

HotJobs.com
Extensive national job site with tens of thousands of searchable job listings.

1to1Jobs.com
Excellent job site with a CRM focus from the Peppers and Rogers Group. Offers personal attention.

JobOptions.com
Easy to use site lets you search of thousands of national job listings.

JobBank USA
Convenient meta search engine searches multiple national job sites (also International sites).

CareerNET
Excellent searchable national job site with job postings ranging from career opportunities to internships.

6FigureJobs.com
Valuable site for senior professionals and executives provides search for both national and international jobs. 

Project Management Institute
Professional association for project management professional with national and international job listings.

JobTrak
Helpful site for students or alumni of many US colleges and universities. Free, but requires a password from your school.

Vault Job Board
Helpful job site with thousands of job postings also lets you optionally exclude recuiter/search firm postings from your results. 

NationJob Online Jobs site
Well designed site with thousands of jobs. National listings with a Midwest focus. Offers unique search and automatic updating for new positions via e-mail.

CareerSite
Easy to use search engine on this well designed site.